During DNA replication, which nucleotide binds to an A nucleotide in the parental DNA strand?

In DNA replication, adenine (A) on the parental DNA strand pairs with thymine (T) in the new complementary strand. This specific pairing is due to the hydrogen bonding ability between the bases: adenine forms two hydrogen bonds with thymine. This ensures that the genetic information is copied accurately, maintaining the integrity of the DNA sequence during replication. The specificity of base pairing is critical for the accurate duplication of DNA, as it allows for the preservation of the genetic code from one generation to the next. In the context of the other potential matches, cytosine (C) and guanine (G) pair with each other, while uracil (U) is not involved in DNA but is crucial in RNA, further emphasizing the pairing specificity between adenine and thymine in the DNA structure.