What type of reaction would you classify as exergonic, where larger molecules are broken down?

The correct classification for a reaction in which larger molecules are broken down is catabolic. Catabolic reactions are a type of metabolic reaction that involves the breakdown of complex molecules into simpler ones, releasing energy in the process. This energy release is what makes these reactions exergonic.

In contrast, endergonic reactions require an input of energy to proceed, often involving the synthesis of larger molecules from smaller ones. Synthetic reactions, which are not synonymous with catabolic reactions, also require energy to combine smaller units into a larger molecule. Oxidative reactions can sometimes be involved in catabolism, particularly in energy production pathways, but they do not inherently refer to the breakdown of larger molecules.

Thus, catabolic processes specifically align with the characteristic of breaking down larger molecules while releasing energy, clearly categorizing them as exergonic.